France Dufresne

Associate Professor,
Université du Québec à Rimouski

Département de Biologie
300, allée des Ursulines, C. P. 3300
Rimouski, Québec
Tel: 418-723-1986 poste 1223
Fax: 418-724-1849
Institution page

Postdoctorate - Population genetics : 1999,Scripps Institute of Oceanography
Postdoctorate - Population genetics: 1998, Université Laval
Doctorate - Zoology: 1995, University of Guelph
Master's - Biologie:1990, Université Laval
Bachelor's: 1987, McGill University

The various kinds of research done in my lab all use different levels of organisation to answer questions of evolutionary biology. My current work is focused on the evolutionary aspects linked to polyploidy in caldocerans. We examine the effects of chromosome duplication on the physiology and ecology of freshwater invertebrates. Thanks to genome sequencing of the water flea, Daphnia pulex, we have new tools to characterize genomes. Additionally, we are interested in genes that control the body size of the daphnia. This characteristic is crucial to evolutionary biology because it is linked to reproductive fitness and curiously, we do not know much about the genes that control it. I am also interested in the factors linked to the origin and maintenance of asexuality. Why do asexual organisms show a different geographical distribution than their asexual ancestors? Certain daphnia clones find themselves in pristine arctic environments and are used to test the different evolutionary hypotheses. The approaches that I use in my lab are to answer these questions using a combination of molecular techniques, metabolic measures as well as experiments.

QCBS students
Previous students (since 2009)
Philippe Boucher, Ph.D.
(Start: 2007, End: 2010)
Thesis title: Génomique écologique et adaptation à la température chez Daphnia pulex
Dominique Hamel, Ph.D.
(Start: 2004, End: 2010)
Other (co-)supervisor: André Rochon
Thesis title: Diversité génétique chez Alexandrium tamarense de l'estuaire du Saint-Laurent
Adriana Radulovici, Ph.D.
(Start: 2006, End: 2012)
Thesis title: Barcoding et structure génétique des amphipodes marins
Geneviève Coté, M.Sc.
(Start: 2010, End: 2015)

Other (co-)supervisor: Rémy Rochette, Université du Nouveau-Brunswick à Saint-Jean
Jean-Michel Martin, M.Sc.
(Start: 2014, End: 2016)

Thesis title: Ploidy's and UV Rays Exposure's Effect on Pigmentation's Plasticity of Arctic Daphnia
Sophie Mercier, M.Sc.
(Start: 2012, End: 2014)
Other QCBS (co-)supervisor: Pierre Blier
Frédérique Paquin, M.Sc.
(Start: 2013, End: 2017)

Thesis title: Du génotype au phénotype: effets des contaminants métalliques sur l'accumulation de mutations et le métabolisme mitochondrial des Daphnia pulex
Thierry Ratté, M.Sc.
(Start: 2006, End: 2010)
Thesis title: Croissance et métabolisme à différentes températures en fonction de la ploïdie chez les daphnies
Gaëlle Van Dijk, M.Sc.
(Start: 2013, End: 2015)
Other QCBS (co-)supervisor: Pierre Blier
Thesis title: Heritability of antioxidant capacity in threespine stickleback Gasterosteus aculeatus
BIO-322-91 - Génétique (Fall / Automne)
BIO-411-99 - Biologie moléculaire et du développement (Fall / Automne)
BIO-412-05 - Écologie moléculaire (Fall / Automne)
FAU-725-05 - Génétique de la conservation (Fall / Automne)
BIO 411 10 - Développement et évolution (Fall / Automne)
FAU 728 16 - Biodiversité et conservation (Fall / Automne)
FAU 711 16 - Communication scientifique (Fall / Automne)

45- Thermal tolerance and thermal sensitivity of heart mitochondria: Mitochondrial integrity and ROS production
Christen F., Desrosiers V., Dupont-Cyr B.A., Vandenberg G.W., Le François N.R., Tardif J., Dufresne F., Lamarre S.G., Blier P.U.
2018 Free Radical Biology and Medicine (Date Added: 2018-01-19)

44- Molecular phylogeny of the genus Themisto (GuCrossed D sign©rin, 1925) (Amphipoda: Hyperiidae) in the Northern Hemisphere
Tempestini A., Fortier L., Pinchuk A., Dufresne F.
2017 Journal of Crustacean Biology (Date Added: 2018-01-19)

43- Temperature-related differences in mitochondrial function among clones of the cladoceran Daphnia pulex
Kake-Guena S., Touisse K., Warren B., Scott K., Dufresne F., Blier P., Lemieux H.
2017 Journal of Thermal Biology (Date Added: 2017-06-24)

42- Eicosapentaenoic acid monoglyceride resolves inflammation in an ex vivo model of human peripheral blood mononuclear cell
Morin C., Charbonneau L., Ouellet N., Ouellet H., Blier P.U., Dufresne F., Fortin S.
2017 European Journal of Pharmacology (Date Added: 2017-06-08)

41- Association between clonal diversity and species diversity in subarctic zooplankton communities
Dionne K., Jose C., Caron A., Dufresne F.
2017 Journal of Plankton Research (Date Added: 2017-04-17)

40- Overlapping trophic niches among co-occurring amphipods from a cryptic species complex
Dionne K., Dufresne F., Nozais C.
2017 Freshwater Biology (Date Added: 2017-04-12)

39- Variation in δ13C and δ15N trophic enrichment factors among Hyalella azteca amphipods from different lakes
Dionne, K., Dufresne, F., Nozais, C.
2016 Hydrobiologia (Date Added: 2016-08-01)

38- Don't throw the baby out with the bathwater: identifying and mapping paralogs in salmonids
Dufresne, F.
2016 Molecular Ecology Resources (Date Added: 2016-02-01)

37- Quantitative variation for metabolic traits among brook trout populations inhabiting different environments: Variation for metabolic traits in brook trout
Dufresne, F., Barroux, A., DitleCadet, D., Blier, P.U.
2015 Journal of Zoology (Date Added: 2015-09-08)

36- Assessment of mitochondrial functions in Daphnia pulex clones using high-resolution respirometry
Kake-Guena, S.A., Touisse, K., Vergilino, R., Dufresne, F., Blier, P.U., Lemieux, H.
2015 Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology (Date Added: 2015-07-10)

35- Climate Effects on High Latitude Daphnia via Food Quality and Thresholds
Przytulska, A., Bartosiewicz, M., Rautio, M., Dufresne, F., Vincent, W.F.
2015 PloS one (Date Added: 2015-06-01)

34- Impact of ploidy level on the distribution of Pokey element insertions in the Daphnia pulex complex
Vergilino, Roland, Eagle, Shannon HC, Crease, Teresa J, Dufresne, France
2014 Mobile DNA (Date Added: 2014-08-21)

33- First record of the green microalgae Coccomyxa sp. in blue mussel Mytilus edulis (L.) from the Lower St. Lawrence Estuary (Québec, Canada)
Zuykov, Michael, Belzile, Claude, Lemaire, Nicolas, Gosselin, Michel, Dufresne, France, Pelletier, Emilien
2014 Journal of Invertebrate Pathology (Date Added: 2014-08-21)

32- Mitochondrial Capture Misleads about Ecological Speciation in the Daphnia pulex Complex
Markova S, Dufresne F, Manca M & P Kotlik
2013 PLoS ONE (Date Added: 2016-06-22)

31- Evolution of a transposon in Daphnia hybrid genomes
Vergilino, R, Elliott, Tyler A, Desjardins-Proulx, P, Crease, TJ, & F. Dufresne
2013 MOBILE DNA (Date Added: 2016-06-22)

30- Recent progress and challenges in population genetics of polyploid organisms: an overview of current state-of-the-art molecular and statistical tools
Dufresne, France, Stift, Marc, Vergilino, Roland, Mable, Barbara K.
2013 Molecular Ecology (Date Added: 2013-11-27)

29- Genome size differences in Hyalella cryptic species
Vergilino, R., Dionne, K., Nozais, C., Dufresne, F., Belzile, C.
2012 Genome / National Research Council Canada = Genome / Conseil National de Recherches Canada (Date Added: 2016-07-11)

28- Pyganodon (Bivalvia: Unionoida: Unionidae) phylogenetics: a male- and female-transmitted mitochondrial DNA perspective
Doucet-Beaupré, Hélène, Blier, Pierre U, Chapman, Eric G, Piontkivska, Helen, Dufresne, France, Sietman, Bernard E, Mulcrone, Renee S, Hoeh, Walter R
2012 Molecular phylogenetics and evolution (Date Added: 2012-07-04)

27- No evidence for temporal variation in a Cryptic species community of freshwater amphipods of the Hyalella azteca species complex
Dionne, K., Vergilino, R., Dufresne, F., Charles, F., Nozais, C.
2011 Diversity (Date Added: 2015-02-19)

26- The History of the Daphnia Pulex complex: Asexuality, Hybridization, And Polyploidy
2011 Phylogeography and population genetics in Crustacea (Date Added: 2012-09-15)

25- Diversity in the Reproductive Modes of European Daphnia pulicaria Deviates from the Geographical Parthenogenesis
Dufresne, France, Marková, Silvia, Vergilino, Roland, Ventura, Marc, Kotlík, Petr
2011 PLoS ONE (Date Added: 2012-07-04)

24- Spatial variation in food availability predicts extrapair paternity in the arctic fox
Cameron, C., Berteaux, D., Dufresne, F.
2011 Behavioral Ecology (Date Added: 2012-07-04)

23- DNA Barcodes for Marine Biodiversity: Moving Fast Forward?
Radulovici, Adriana E., Archambault, Philippe, Dufresne, France
2010 Diversity (Date Added: 2012-07-04)

22- Unusual duplication of the insulin-like receptor in the crustacean Daphnia pulex
Boucher, Philippe, Ditlecadet, Delphine, Dubé, Caroline, Dufresne, France
2010 BMC Evolutionary Biology (Date Added: 2012-07-04)

21- Differential survival among genotypes of Daphnia pulex differing in reproductive mode, ploidy level, and geographic origin
Jose, Caroline, Dufresne, France
2009 Evolutionary Ecology (Date Added: 2012-07-04)

20- DNA barcoding of marine crustaceans from the Estuary and Gulf of St Lawrence: a regional-scale approach
Radulovici, Adriana E, Sainte-Marie, Bernard, Dufresne, France
2009 Molecular ecology resources (Date Added: 2012-07-04)

19- Genome size evolution and polyploidy in the Daphnia pulex complex (Cladocera: Daphniidae)
Vergilino, Roland, Belzile, Claude, Dufresne, France
2009 Biological Journal of the Linnean Society (Date Added: 2012-07-04)

18- Low flexibility of metabolic capacity in subarctic and temperate cytotypes of Daphnia pulex
Jose, Caroline, Chatelain, Étienne Hébert, Dufresne, France
2009 Journal of Thermal Biology (Date Added: 2012-07-04)

17- Do territorial male three-spined sticklebacks have sperm with different characteristics than nonterritorial males?
Côté, J., Blier, P.U., Caron, A., Dufresne, F.
2009 Canadian Journal of Zoology (Date Added: 2012-05-10)

16- Digestive capacities, inbreeding and growth capacities in juvenile Arctic charr Salvelinus alpinus
Ditlecadet, D., Blier, P.U., Le François, N.R., Dufresne, F.
2009 Journal of Fish Biology (Date Added: 2012-05-10)

15- Plasticity of growth rate and metabolism in Daphnia magna populations from different thermal habitats
Chopelet, J., Blier, P.u., Dufresne, F.
2008 Journal of Experimental Zoology Part A: Ecological Genetics and Physiology (Date Added: 2012-07-24)

14- Large genomes among caridean shrimp
Rees, David J, Belzile, Claude, Glémet, Hélène, Dufresne, France
2008 Genome / National Research Council Canada = Génome / Conseil national de recherches Canada (Date Added: 2012-07-04)

13- Cryptic intercontinental colonization in water fleas Daphnia pulicaria inferred from phylogenetic analysis of mitochondrial DNA variation
Marková, Silvia, Dufresne, France, Rees, David J., ?erný, Martin, Kotlík, Petr
2007 Molecular Phylogenetics and Evolution (Date Added: 2012-07-24)

12- Amphipod genome sizes: first estimates for Arctic species reveal genomic giants
Rees, David J., Dufresne, France, Glémet, Hélène, Belzile, Claude
2007 Genome (Date Added: 2012-07-24)

11- Applying microsatellites in two commercial strains of Arctic charr (Salvelinus alpinus): Potential for a selective breeding program
Ditlecadet, Delphine, Dufresne, France, Le François, Nathalie Rose, Blier, Pierre Ulrich
2006 Aquaculture (Date Added: 2012-07-24)

10- Morphological variation in Nereis (Neanthes) virens (Polychaeta: Nereididae) populations
Breton, S., Dufresne, F., Desrosiers, G., Blier, P.
2004 Journal of the Marine Biological Association of the United Kingdom (Date Added: 2014-02-19)

9- Population structure of two northern hemisphere polychaetes, Neanthes virens and Hediste diversicolor (Nereididae), with different life-history traits
Breton, S., Dufresne, F., Desrosiers, G., Blier, P.U.
2003 Marine Biology (Date Added: 2014-02-19)

7- Natural selection and the evolution of mtDNA-encoded peptides: evidence for intergenomic co-adaptation
Blier, Pierre U, Dufresne, France, Burton, Ronald S
2001 Trends in Genetics (Date Added: 2012-07-24)

6- Isolation and characterization of microsatellite markers in the acorn barnacle Semibalanus balanoides
Dufresne, France, Parent, Madeleine, Bernatchez, Louis
1999 Molecular Ecology (Date Added: 2012-07-24)

5- Pleistocene glaciations and polyphyletic origins of polyploidy in an arctic cladoceran
Dufresne, France, Hebert, Paul D. N.
1997 Proceedings of the Royal Society B: Biological Sciences (Date Added: 2012-07-24)

4- Metabolism and habitat competition in the polychaete Nereis virens
Lemieux, H., Blier, P.U., Dufresne, F., Desrosiers, G.
1997 Marine Ecology Progress Series (Date Added: 2012-05-10)

3- Polyploidy and clonal diversity in an arctic cladoceran
Dufresne, France, Hebert, Paul
1995 Heredity (Date Added: 2012-07-24)

2- Hybridization and Origins of Polyploidy
Dufresne, France, Hebert, Paul D. N.
1994 Proceedings of the Royal Society B: Biological Sciences (Date Added: 2012-07-24)

1- Atomic models for the polypeptide backbones of myohemerythrin and hemerythrin
Hendrickson, W. A., Ward, K. B.
1975 Biochemical and Biophysical Research Communications (Date Added: 2014-08-21)