Inès Levade

Université de Montréal
Candidat Ph.D.

superviseur(e): Jesse Shapiro
Début: 2014-01-01
Fin: 2020-04-30


Genomic analysis of cholera micro-evolution and transmission
Cholera is a severe, waterborne diarrheal disease that affects millions of people each year. Recent advances in bacterial genomics have rapidly altered our understanding of the macroevolution of Vibrio cholerae, the causative agent of this disease, but little is known about its short-term evolution, within households and within individuals. The goal of my research is to characterize V. cholerae genomic diversity at a spatial and temporal scale relevant to micro-epidemics, following a population genomic approach that can provide insights into the transmission and adaptation of this pathogen.


1- Population genomics ofMycobacterium tuberculosisin the Inuit
Lee, Robyn S., Nicolas Radomski, Jean-Francois Proulx, Ines Levade, B. Jesse Shapiro, Fiona McIntosh, Hafid Soualhine, Dick Menzies, Marcel A. Behr
2015 Proceedings of the National Academy of Sciences

2- Origins of pandemic Vibrio cholerae from environmental gene pools
Shapiro, B. Jesse, Inès Levade, Gabriela Kovacikova, Ronald K. Taylor, Salvador Almagro-Moreno
2016 Nature Microbiology