Sophie Breton
Associate Professor,Université de Montréal
Department of Biology
E-mail: s.breton@umontreal.ca
Institution page
Education
ResearchMy research program is integrative, using approaches including molecular biology, physiology, genomics, transcriptomics, proteomics and evolutionary biology to address the following questions: How do new species form? How do organisms adapt to their environment? My team is particularly interested to better understand the role of mitochondria and their genomes in speciation. In this perspective, my research aims at better understand the function, structure, expression, evolution and inheritance of mitochondrial genomes, the co-adaptation of mitochondrial and nuclear genomes and the physiological mechanisms of animal adaptation to environmental conditions.Prizes and honoursMédaille d'or académique du Gouverneur Général du Canada, 2003 QCBS studentsAlizée DebelliM.Sc. Laura KienzleM.Sc. Ariane Pouliot-DrouinM.Sc. Previous students (since 2009)Stefano BettinazziPh.D. Christelle LeungPh.D. Karim BouvetM.Sc. Émélie LerouxM.Sc. Alyssa MitchellM.Sc. Mélanie TasséM.Sc. Involvement within the QCBSRelevant QCBS research themesExamples of species studiedMytilus Venustaconcha ellipsiformis Bivalvia Unionoida Mytilus edulis Mytilidae Mollusca Nereididae Neanthes virens Hediste diversicolor Ruditapes philippinarum Veneridae Modiolus modiolus Unionida Chaetopleura apiculata Chaetopleuridae Anodonta cygnea Unionidae Publications42- Evaluating the utility of the femalespecific mitochondrial f-orf gene for population genetic, phylogeographic and systematic studies in freshwater mussels (Bivalvia: Unionida) Journal Article Robicheau B M , Chase E E , Hoeh W R , Harris J L , Stewart D T , Breton S , 2018 PeerJ (Date Added: 2018-06-27) 41- Actively transcribed and expressed atp8 gene in Mytilus edulis mussels Journal Article LuboÅ›ny M , PrzyÅ‚ucka A , Åšmietanka B , Breton S , BurzyÅ„ski A , 2018 PeerJ (Date Added: 2018-06-22) 40- Mitochondrial activity in gametes and uniparental inheritance: a comment on 'What can we infer about the origin of sex in early eukaryotes?' Journal Article Ghiselli, F, Breton, S, Milani, L 2018 Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences (Date Added: 2018-05-07) 39- Distribution and frequency of mitochondrial DNA polymorphisms in Blue Mussel (Mytilus edulis) populations of southwestern Nova Scotia (Canada) Journal Article Stewart, D, Sinclair-Waters, M, Rice, A, Bunker, RA, Robicheau, BM, Breton, S 2018 Canadian Journal of Zoology (Date Added: 2018-05-07) 38- Hybrid de novo assembly of the draft genome of the freshwater mussel Venustaconcha ellipsiformis (Bivalvia: Unionida) Journal Article Renaut S, Guerra D, Hoeh WR, Stewart DT, Bogan AE, Ghiselli F, Milani L, Passamonti M, Breton S, 2018 Genome Biology and Evolution (Date Added: 2018-05-07) 37- The complete mitochondrial genome of the hermaphroditic freshwater mussel Anodonta cygnea (Bivalvia: Unionidae): In silico analyses of sex-specific ORFs across order Unionoida Journal Article E E Chase, BMR 2018 BMC Genomics (Date Added: 2018-04-04) 36- Deciphering the Link between Doubly Uniparental Inheritance of mtDNA and Sex Determination in Bivalves: Clues from Comparative Transcriptomics Journal Article Capt C , Renaut S , Ghiselli F , Milani L , Johnson N A , Sietman B E , Stewart D T , Breton S , 2018 Genome Biology and Evolution (Date Added: 2018-03-19) 35- Mitochondrial gene order evolution in Mollusca: Inference of the ancestral state from the mtDNA of Chaetopleura apiculata (Polyplacophora, Chaetopleuridae) Journal Article Guerra D , Bouvet K , Breton S , 2018 Molecular Phylogenetics and Evolution (Date Added: 2018-01-06) 34- The extremely divergent maternally-and paternally-transmitted mitochondrial genomes are co-expressed in somatic tissues of two freshwater mussel species with doubly uniparental inheritance of mtDNA Journal Article Breton S , Bouvet K , Auclair G , Ghazal S , Sietman B E , Johnson N , Bettinazzi S , Stewart D T , Guerra D , 2017 PLoS ONE (Date Added: 2017-08-29) 33- Evolution of sex-dependent mtDNA transmission in freshwater mussels (Bivalvia: Unionida) Journal Article Guerra D , Plazzi F , Stewart D T , Bogan A E , Hoeh W R , Breton S , 2017 Scientific Reports (Date Added: 2017-05-26) 32- No evidence of sex-linked heteroplasmy or doubly-uniparental inheritance of mtDNA in five gastropod species Journal Article Gusman A , Azuelos C , Breton S , 2017 Journal of Molluscan Studies (Date Added: 2017-03-20) 31- Sequence motifs associated with paternal transmission of mitochondrial DNA in the horse mussel, Modiolus modiolus (Bivalvia: Mytilidae) Journal Article Robicheau B M , Breton S , Stewart D T , 2017 Gene (Date Added: 2017-02-15) 30- Evidence for extreme sequence divergence between the male- and female-transmitted mitochondrial genomes in the bivalve mollusc, Modiolus modiolus (Mytilidae) Journal Article Robicheau B M , Powell A E , Del Bel L , Breton S , Stewart D T , 2016 Journal of Zoological Systematics and Evolutionary Research (Date Added: 2017-02-15) 29- Pursuing the quest for better understanding the taxonomic distribution of the system of doubly uniparental inheritance of mtDNA Journal Article Gusman, A, Lecomte, S, Stewart, DT, Passamonti, M, Breton, S 2016 PeerJ (Date Added: 2016-12-22) 28- In silico analyses of mitochondrial ORFans in freshwater mussels (Bivalvia: Unionoida) provide a framework for future studies of their origin and function Journal Article Mitchell, A, Guerra, D, Stewart, D, Breton, S 2016 BMC Genomics (Date Added: 2016-11-28) 27- The human mitochondrial genome may code for more than 13 proteins Journal Article Capt, C, Passamonti, M, Breton, S 2016 Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis (Date Added: 2016-07-06) 26- Facing Environmental Predictability with Different Sources of Epigenetic Variation Journal Article Leung C, BS 2016 Ecology and Evolution (Date Added: 2016-06-23) 25- Early replication dynamics of sex-linked mitochondrial DNAs in the doubly uniparental inheritance species Ruditapes philippinarum (Bivalvia Veneridae) Journal Article Guerra, D, Ghiselli, F, Milani, L, Breton, S, Passamonti, M 2016 Heredity (Date Added: 2016-02-26) 24- Analysis of the coding potential of the ORF in the control region of the female-transmitted Mytilus mtDNA Journal Article Minoiu, I, Burzynski, A, Breton, S 2016 Gene (Date Added: 2016-01-15) 23- Atypical mitochondrial inheritance patterns in eukaryotes Journal Article Breton, S, Stewart, DT 2015 Genome / National Research Council Canada = Genome / Conseil National de Recherches Canada (Date Added: 2015-12-15) 22- A resourceful genome: updating the functional repertoire and evolutionary role of animal mitochondrial DNAs Journal Article Breton, S, Milani, L, Ghiselli, F, Guerra, D, Stewart, DT, Passamonti, M 2014 Trends in Genetics (Date Added: 2014-12-22) 21- Mitochondrial genes, sex determination and hermaphroditism in freshwater mussels (Bivalvia: Unionoida) Journal Article Stewart DT, HW 2013 Evolutionary Biology: Exobiology and Evolutionary Mechanisms (Date Added: 2016-06-20) 20- Structure, transcription, and variability of metazoan mitochondrial genome: Perspectives from an unusual mitochondrial inheritance system Journal Article Ghiselli, F, Milani, L, Guerra, D, Chang, PL, Breton, S, Nuzhdin, SV, Passamonti, M 2013 Genome Biology and Evolution (Date Added: 2014-02-19) 19- Population genetics of sex determination in Mytilus mussels: Reanalyses and a model Journal Article Yusa, Y, Breton, S, Hoeh, WR 2013 Journal of Heredity (Date Added: 2014-02-19) 18- A comparative analysis of mitochondrial ORFans: New clues on their origin and role in species with Doubly Uniparental Inheritance of mitochondria Journal Article Milani, L, Ghiselli, F, Guerra, D, Breton, S, Passamonti, M 2013 Genome Biology and Evolution (Date Added: 2014-02-19) 17- Light and Transmission Electron Microscopy of Two Spermatogenic Pathways and Unimorphic Spermatozoa in Venustaconcha ellipsiformis (Conrad, 1836) (Bivalvia: Unionoida) Journal Article Shepardson, SP, Heard, WH, Breton, S, Hoeh, WR 2012 Malacologia (Date Added: 2014-03-11) 16- Unscrambling genetic information at the RNA level Journal Article Moreira, S, Breton, S, Burger, G 2012 Wiley Interdisciplinary Reviews: RNA (Date Added: 2014-02-19) 15- No effect of sperm interactions or egg homogenate on sperm velocity in the blue mussel, Mytilus edulis (Bivalvia: Mytilidae) Journal Article Stewart, DT, Jha, M, Breton, S, Randolph Hoeh, W, Blier, PU 2012 Canadian Journal of Zoology (Date Added: 2014-02-19) 14- Evidence for a fourteenth mtDNA-encoded protein in the female-transmitted mtDNA of marine mussels (Bivalvia: Mytilidae) Journal Article Breton, S, Ghiselli, F, Passamonti, M, Milani, L, Stewart, DT, Hoeh, WR 2011 PLoS ONE (Date Added: 2014-02-19) 13- Novel protein genes in animal mtDNA: A new sex determination system in freshwater mussels (Bivalvia: Unionoida)? Journal Article Breton, S, Stewart, DT, Shepardson, S, Trdan, RJ, Bogan, AE, Chapman, EG, Ruminas, AJ, Piontkivska, H, Hoeh, WR 2011 Molecular Biology and Evolution (Date Added: 2014-02-19) 12- Mitochondrial phylogenomics of the Bivalvia (Mollusca): Searching for the origin and mitogenomic correlates of doubly uniparental inheritance of mtDNA Journal Article Doucet-Beaupré, H, Breton, S, Chapman, EG, Blier, PU, Bogan, AE, Stewart, DT, Hoeh, WR 2010 BMC Evolutionary Biology (Date Added: 2014-02-19) 11- Thermal sensitivity of metabolic enzymes in subarctic and temperate freshwater mussels (Bivalvia: Unionoida) Journal Article Doucet-Beaupré, H, Dubé, C, Breton, S, Pörtner, HO, Blier, PU 2010 Journal of Thermal Biology (Date Added: 2014-02-19) 10- Characterization of a mitochondrial ORF from the gender-associated mtDNAs of Mytilus spp. (Bivalvia: Mytilidae): Identification of the "missing" ATPase 8 gene Journal Article Breton, S, Stewart, DT, Hoeh, WR 2010 Marine Genomics (Date Added: 2014-02-19) 9- Role-reversal of gender-associated mitochondrial dna affects mitochondrial function in mytilus edulis (bivalvia: mytilidae) Journal Article Breton, S, Stewart, DT, Blier, PU 2009 Journal of Experimental Zoology Part B: Molecular and Developmental Evolution (Date Added: 2014-02-19) 8- Comparative mitochondrial genomics of freshwater mussels (Bivalvia: Unionoida) with doubly uniparental inheritance of mtDNA: Gender-specific open reading frames and putative origins of replication Journal Article Breton, S, Beaupré, HD, Stewart, DT, Piontkivska, H, Karmakar, M, Bogan, AE, Blier, PU, Hoeh, WR 2009 Genetics (Date Added: 2014-02-19) 7- Epitoky in Nereis (Neanthes) virens (Polychaeta: Nereididae): A story about sex and death Journal Article Hébert Chatelain, Ã, Breton, S, Lemieux, H, Blier, PU 2008 Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology (Date Added: 2014-02-19) 6- The unusual system of doubly uniparental inheritance of mtDNA: isn't one enough? Journal Article Breton, S, Beaupré, HD, Stewart, DT, Hoeh, WR, Blier, PU 2007 Trends in Genetics (Date Added: 2014-02-19) 5- Un système de transmission de l'ADN mitochondrial sexuellement équitable = A sexually fair system of mitochondrial DNA transmission Journal Article Breton, S, Beaupré, HD 2007 Médecine Sciences (Date Added: 2014-02-19) 4- Comparative analysis of gender-associated complete mitochondrial genomes in marine mussels (Mytilus spp.) Journal Article Breton, S, Burger, G, Stewart, DT, Blier, PU 2006 Genetics (Date Added: 2014-02-19) 3- Functional conservatism in mitochondrial evolution: Insight from hybridization of arctic and brook charrs Journal Article Blier, PU, Breton, S, Desrosiers, V, Lemieux, H 2006 Journal of Experimental Zoology Part B: Molecular and Developmental Evolution (Date Added: 2014-02-19) 2- Morphological variation in Nereis (Neanthes) virens (Polychaeta: Nereididae) populations Journal Article Breton, S, Dufresne, F, Desrosiers, G, Blier, P 2004 Journal of the Marine Biological Association of the United Kingdom (Date Added: 2014-02-19) 1- Population structure of two northern hemisphere polychaetes, Neanthes virens and Hediste diversicolor (Nereididae), with different life-history traits Journal Article Breton, S, Dufresne, F, Desrosiers, G, Blier, PU 2003 Marine Biology (Date Added: 2014-02-19) In the mediaQuelle influence ont les vers parasites sur la consommation d’oxygène des crapets-soleils? 2024-07-25 How do parasitic worms affect the oxygen uptake of sunfish? 2024-07-25 Une subvention de plus de 230 000 $ pour mieux comprendre de nouveaux gènes 2024-06-20 Hidden gene pokes holes in preconceptions (Catherine Couturier) 2023-07-11 Pourquoi certains animaux hibernent-ils? (Techno-Science) 2015-04-01 Pourquoi certains animaux hibernent-ils? Techno-science 2015-04-01 Mitochondrie, l'étranger dans la maison (1/4) / Québec Science (Lumbroso, sylvain) 2015-04-01 Enquête sur le sexe des moules. Québec Science 2013-00-00 |