Sarah Otto
Professeur titulaire,University of British Columbia
Department of Zoology
Courriel: otto@zoology.ubc.ca
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RechercheL'objectif motivant mes recherches est de comprendre comment les processus évolutifs ont généré la merveilleuse diversité des caractéristiques biologiques observées dans le monde naturel. Pourquoi certaines espèces se reproduisent-elles asexuellement, alors que la plupart se reproduisent sexuellement ? Pourquoi certains organismes ont-ils de grands génomes alors que des espèces étroitement apparentées en ont de petits ? Pourquoi certaines espèces choisissent-elles de s'accoupler avec des partenaires très semblables, alors que d'autres les évitent ? Ce sont là quelques-unes des questions fondamentales que mes recherches visent à résoudre, en combinant la théorie mathématique, l'inférence statistique et les expériences sur l'évolution.Exemples d'espèces étudiéesCrassostrea gigas Publications38- Variety is the spice of life: nongenetic variation in life histories influences population growth and evolvability Journal Article Forsythe A B , Otto S P , Nelson W A , Day T , 2024 Journal of Evolutionary Biology (Date Added: 2024-11-14) 37- Planting long-lived trees in a warming climate: Theory shows the importance of stage-dependent climatic tolerance Journal Article Erlichman A , Sandell L , Otto S P , Aitken S N , Ronce O , 2024 Evolutionary Applications (Date Added: 2024-06-24) 36- Endemic does not mean constant as SARS-CoV-2 continues to evolve Journal Article Otto S P , MacPherson A , Colijn C , 2024 Evolution (Date Added: 2024-06-08) 35- Endemic does not mean constant as SARS-CoV-2 continues to evolve Journal Article Otto S P , MacPherson A , Colijn C , 2024 Evolution (Date Added: 2024-06-08) 34- Endemic does not mean constant as SARS-CoV-2 continues to evolve Journal Article Otto S P , MacPherson A , Colijn C , 2024 Evolution (Date Added: 2024-06-08) 33- Endemic does not mean constant as SARS-CoV-2 continues to evolve Journal Article Otto S P , MacPherson A , Colijn C , 2024 Evolution (Date Added: 2024-06-08) 32- Modelling daisy quorum drive: A short-term bridge across engineered fitness valleys Journal Article de Haas F J H , Kläy L , Débarre F , Otto S P , 2024 PLoS Genetics (Date Added: 2024-05-25) 31- Corrigendum to “Fixation and effective size in a haploid–diploid population with asexual reproduction” [Theoretical Population Biology 143 (2022) 30–45, (S0040580921000769), (10.1016/j.tpb.2021.11.002)] Journal Erratum Bessho K , Otto S P , 2024 Theoretical Population Biology (Date Added: 2024-05-08) 30- The prokaryotic and eukaryotic microbiome of Pacific oyster spat is shaped by ocean warming but not acidification Journal Article Zhong K X , Chan A M , Collicutt B , Daspe M , Finke J F , Foss M , Green T J , Harley C D G , Hesketh A V , Miller K M , Otto S P , Rolheiser K , Saunders R , Sutherland B J G , Suttle C A , 2024 Applied and Environmental Microbiology (Date Added: 2024-04-26) 29- When and how can we predict adaptive responses to climate change? Journal Article Urban M C , Swaegers J , Stoks R , Snook R R , Otto S P , Noble D W A , Moiron M , Hällfors M H , Gómez-Llano M , Fior S , Cote J , Charmantier A , Bestion E , Berger D , Baur J , Alexander J M , Saastamoinen M , Edelsparre A H , Teplitsky C , 2024 Evolution Letters (Date Added: 2024-03-01) 28- On the fast track: hybrids adapt more rapidly than parental populations in a novel environment Journal Article Kulmuni J , Wiley B , Otto S P , 2024 Evolution Letters (Date Added: 2024-03-01) 27- Density-Dependent Selection during Range Expansion Affects Expansion Load in Life History Traits Journal Article Urquhart-Cronish M , Angert A L , Otto S P , MacPherson A , 2024 The American naturalist (Date Added: 2024-02-26) 26- Effective pandemic policy design through feedback does not need accurate predictions Journal Article van Heusden K , Stewart G E , Otto S P , Dumont G A , 2023 PLOS Global Public Health (Date Added: 2024-06-13) 25- Conceptual and empirical bridges between micro- and macroevolution Journal Article Rolland J , Henao-Diaz L F , Doebeli M , Germain R , Harmon L J , Knowles L L , Liow L H , Mank J E , Machac A , Otto S P , Pennell M , Salamin N , Silvestro D , Sugawara M , Uyeda J , Wagner C E , Schluter D , 2023 Nature Ecology and Evolution (Date Added: 2023-07-22) 24- Braiding Indigenous rights and endangered species law Journal Article Lamb C T , Willson R , Menzies A K , Owens-Beek N , Price M , McNay S , Otto S P , Hessami M , Popp J N , Hebblewhite M , Ford A T , 2023 Science (New York, N.Y.) (Date Added: 2023-07-04) 23- Trait-dependent diversification in angiosperms: Patterns, models and data Journal Article Helmstetter A J , Zenil‐Ferguson R , Sauquet H , Otto S P , Méndez M , Vallejo‐Marin M , Schönenberger J , Burgarella C , Anderson B , de Boer H , Glémin S , Käfer J , 2023 Ecology Letters (Date Added: 2023-07-04) 22- Opposing effects of plant traits on diversification Journal Article Anderson B , Pannell J , Billiard S , Burgarella C , de Boer H , Dufay M , Helmstetter A J , Méndez M , Otto S P , Roze D , Sauquet H , Schoen D , Schönenberger J , Vallejo-Marin M , Zenil-Ferguson R , Käfer J , Glémin S , 2023 iScience (Date Added: 2023-04-03) 21- Rapid weed adaptation and range expansion in response to agriculture over the past two centuries Journal Article Kreiner J M , Latorre S M , Burbano H A , Stinchcombe J R , Otto S P , Weigel D , Wright S I , 2022 Science (Date Added: 2023-07-04) 20- The phoenix hypothesis of speciation Journal Article Yamaguchi R , Wiley B , Otto S P , 2022 Proceedings of the Royal Society B: Biological Sciences (Date Added: 2022-11-27) 19- The best of both worlds: Combining population genetic and quantitative genetic models Journal Article Dekens L , Otto S , Calvez V , 2022 Theoretical Population Biology (Date Added: 2022-11-21) 18- Unbalanced selection: The challenge of maintaining a social polymorphism when a supergene is selfish Journal Article Tafreshi A G , Otto S P , Chapuisat M , 2022 Philosophical Transactions of the Royal Society B: Biological Sciences (Date Added: 2022-07-12) 17- Parental Population Range Expansion before Secondary Contact Promotes Heterosis Journal Article MacPherson A , Wang S , Yamaguchi R , Rieseberg L H , Otto S P , 2022 American Naturalist (Date Added: 2022-06-08) 16- Savannas are vital but overlooked carbon sinks Journal Article Dobson A , Hopcraft G , Mduma S , Ogutu J O , Fryxell J , Anderson T M , Archibald S , Lehmann C , Poole J , Caro T , Mulder M B , Holt R D , Berger J , Rubenstein D I , Kahumbu P , Chidumayo E N , Milner-Gulland E J , Schluter D , Otto S , Balmford A , Wilcove D , Pimm S , Veldma J , Olff H , Noss R , Holdo R , Beale C , Hempson G , Kiwango Y , Lindenmayer D , Bond W , Ritchie M , Sinclair A R E , 2022 Science (Date Added: 2022-03-20) 15- Fixation and effective size in a haploid–diploid population with asexual reproduction Journal Article Bessho K , Otto S P , 2022 Theoretical Population Biology (Date Added: 2022-01-04) 14- Fundamental limitations of contact tracing for COVID-19 Journal Article Tupper P , Otto S P , Colijn C , 2021 Facets (Date Added: 2022-03-20) 13- The virus evolves: Four public health priorities for reducing the evolutionary potential of SARS-CoV-2 Journal Article Fitzpatrick C L , Alter S E , Boughman J W , Débarre F , Edmands S , Moehring A , Moyle L , Otto S P , Ronce O , Rubin M J , Sweigart A L , 2021 BioScience (Date Added: 2022-03-20) 12- An Empiricist’s Guide to Using Ecological Theory Journal Article Grainger, TN, Senthilnathan, A, Ke, P-J, Barbour, MA, Jones, NT, Delong, JP, Otto, SP, O’connor, MI, Coblentz, KE, Goel, N, Sakarchi, J, Szojka, MC, Levine, JM, Germain, RM 2021 American Naturalist (Date Added: 2021-12-12) 11- The origins and potential future of SARS-CoV-2 variants of concern in the evolving COVID-19 pandemic Journal Article Otto S P , Day T , Arino J , Colijn C , Dushoff J , Li M , Mechai S , Van Domselaar G , Wu J , Earn D J , Ogden N H , 2021 Current Biology (Date Added: 2021-11-05) 10- Evolution of plasticity in production and transgenerational inheritance of small RNAs under dynamic environmental conditions Journal Article Silva W T A F , Otto S P , Immler S , 2021 PLoS Genetics (Date Added: 2021-11-05) 9- Feedback between coevolution and epidemiology can help or hinder the maintenance of genetic variation in host-parasite models Journal Article MacPherson A , Keeling M J , Otto S P , 2021 Evolution (Date Added: 2021-11-05) 8- Selective Interference and the Evolution of Sex Journal Article Otto S P , 2021 The Journal of heredity (Date Added: 2021-11-05) 7- Coevolution fails to maintain genetic variation in a host–parasite model with constant finite population size Journal Article MacPherson A , Keeling M J , Otto S P , 2021 Theoretical Population Biology (Date Added: 2021-11-05) 6- On the Origin of Coexisting Species Journal Article Germain R M , Hart S P , Turcotte M M , Otto S P , Sakarchi J , Rolland J , Usui T , Angert A L , Schluter D , Bassar R D , Waters M T , Henao-Diaz F , Siepielski A M , 2021 Trends in Ecology and Evolution (Date Added: 2021-11-05) 5- On the evolutionary epidemiology of SARS-CoV-2 Journal Article Day T , Gandon S , Lion S , Otto S P , 2020 Current Biology (Date Added: 2021-11-05) 4- Relative genomic impacts of translocation history, hatchery practices, and farm selection in Pacific oyster Crassostrea gigas throughout the Northern Hemisphere Journal Article Sutherland B J G , Rycroft C , Ferchaud A , Saunders R , Li L , Liu S , Chan A M , Otto S P , Suttle C A , Miller K M , 2020 Evolutionary Applications (Date Added: 2021-11-05) 3- Genetic paths to evolutionary rescue and the distribution of fitness effects along them Journal Article Osmond M M , Otto S P , Martin G , 2020 Genetics (Date Added: 2021-11-05) 2- Theory in service of narratives in evolution and ecology Journal Article Otto S P , Rosales A , 2020 American Naturalist (Date Added: 2021-11-05) 1- TRY plant trait database – enhanced coverage and open access Journal Article , 2020 Global Change Biology (Date Added: 2020-11-30) |
